Defining hair follicles in the age of stem cell bioengineering.
نویسندگان
چکیده
One challenge faced by stem cell biologists is the bioengineering of an organ. Ehama et al. (2007, this issue) used cells derived from human and rodent epidermis and dermal papilla to reconstitute hair-follicle mini-organs. Some result in hair follicles; others are hair follicle-like. The challenge calls for the development of a set of criteria to define a hair follicle so that bioengineered products in the future can be evaluated.
منابع مشابه
Treatment of segmental vitiligo with normal-hair follicle autograft
Background: Segmental vitiligo is a small subset albeit persistent form of focal vitiligo with dermatomal distribution and resistant to medical therapy. In recent years, surgical therapy as hair follicle autograft transplantation has been a hot topic in management of segmental vitiligo. In this study, we evaluated the efficacy of this method in segmental vitiligo lesions. Methods: Th...
متن کاملStudy on Effect of Head, Tail, and Limbud extracts of Mouse on Differentiation of Hair Follicle Stem Cells to Neural cells
Introduction: Adult stem cells are the group of cells which conserve their nature in tissues and organs among other cells. In recent years, the researchers reported the existence of stem cells on the Bulge of hair follicles near to the smooth muscle. It is possible to differentiate these stem cells to neural cells by induction of Shh, FGF, and RA factors. Because of existence of these factors ...
متن کاملتاثیر غلظت‌های مختلف ال- ترانس رتینوئیک اسید بر رشد و بقای سلول‌های بنیادی فولیکول موی موش سوری
Background and Objective: Hair follicle stem cells are multipotent, located in the bulge area, and are highly proliferating. Retinoids have an effect on epidermal differentiation and keratinization. Retinoic acid is used to treat some skin diseases such as Melasma, Acne and Ichthyosis. So, the study of all-trans retinoic acid effect on hair follicle stem cells and determination of the effective...
متن کاملبررسی اثر پرتوگیری مزمن روی ریزش موی در پرتوکاران در ایران
Abstract Background: Follicles are part of epidermis and pass through a cell cycle. The result of this cell division is producing hair. Follicles specially growing follicles are very sensitive against irradiation and are damaged by low dose rates. So in this study investigated the relationship between chronic exposure of radiation workers and their hair loss. Materials and methods: In this stud...
متن کاملمقایسۀ ساختار و فراساختار فولیکول های مو و پر
Formations of feather and hair follicles during embryonic stage are nearly similar. The aim of the present research is to study the similarities and differences between these two follicles in adult pigeons and rats. To fulfill this task, feather and hair follicles were dissected and processed for light and electron microscopy. The results demonstrated that these two follicles were similar in ha...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- The Journal of investigative dermatology
دوره 127 9 شماره
صفحات -
تاریخ انتشار 2007